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Lei Guo Selected Research

Colorectal Neoplasms (Colorectal Cancer)

12/2023CYP1B1 promotes colorectal cancer liver metastasis by enhancing the growth of metastatic cancer cells via a fatty acids-dependent manner.
10/2022Complement C5 is a novel biomarker for liver metastasis of colorectal cancer.
12/2021Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling.
1/2021Identification of DNA methylation biomarkers for risk of liver metastasis in early-stage colorectal cancer.
1/2021Cytoplasmic MSH2 Related to Genomic Deletions in the MSH2/EPCAM Genes in Colorectal Cancer Patients With Suspected Lynch Syndrome.
8/2020PDCD6 cooperates with C-Raf to facilitate colorectal cancer progression via Raf/MEK/ERK activation.
12/2019Analysis of volatile organic compounds released from SW480 colorectal cancer cells and the blood of tumor-bearing mice.
3/2019NGS-based oncogenic mutations analysis in advanced colorectal cancer patients improves targeted therapy prediction.
1/2019Release of volatile organic compounds (VOCs) from colorectal cancer cell line LS174T.
3/2017Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities.
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Lei Guo Research Topics

Disease

189Neoplasms (Cancer)
05/2024 - 05/2006
36Hepatocellular Carcinoma (Hepatoma)
02/2024 - 10/2009
32Neoplasm Metastasis (Metastasis)
05/2024 - 05/2010
31Infections
01/2024 - 11/2011
29Breast Neoplasms (Breast Cancer)
04/2024 - 05/2006
27Inflammation (Inflammations)
10/2023 - 07/2007
19Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2023 - 08/2013
17Adenocarcinoma of Lung
08/2023 - 03/2014
16Stomach Neoplasms (Stomach Cancer)
09/2022 - 05/2003
14Colorectal Neoplasms (Colorectal Cancer)
12/2023 - 09/2012
14Hypoxia (Hypoxemia)
02/2022 - 06/2008
13Carcinogenesis
01/2024 - 11/2007
13Lung Neoplasms (Lung Cancer)
10/2023 - 09/2012
12Alzheimer Disease (Alzheimer's Disease)
01/2024 - 10/2017
12Osteoporosis
12/2022 - 01/2015
11Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 04/2011
11Hemorrhage
01/2024 - 07/2014
9Parkinson Disease (Parkinson's Disease)
04/2024 - 12/2008
9Cognitive Dysfunction
12/2023 - 01/2018
9Carcinoma (Carcinomatosis)
09/2023 - 05/2010
9Stroke (Strokes)
03/2023 - 10/2007
8Colonic Neoplasms (Colon Cancer)
02/2024 - 11/2014
8Mitochondrial Diseases (Mitochondrial Disease)
12/2023 - 12/2008
8Hypertension (High Blood Pressure)
10/2023 - 08/2010
8Bradycardia
10/2023 - 11/2002
8Bone Resorption
01/2023 - 11/2014
8Neuroinflammatory Diseases
11/2022 - 10/2020
8Death (Near-Death Experience)
01/2021 - 09/2018
7Poisoning
05/2024 - 12/2014
7Sepsis (Septicemia)
01/2024 - 10/2014
7Wounds and Injuries (Trauma)
10/2023 - 04/2016
7Hemangioma (Angioma)
06/2023 - 02/2019
7Asthma (Bronchial Asthma)
01/2022 - 07/2007
7Melanoma (Melanoma, Malignant)
12/2020 - 06/2010
7Chronic Obstructive Pulmonary Disease (COPD)
10/2020 - 02/2012
6Weight Loss (Weight Reduction)
04/2024 - 10/2008
6Renal Cell Carcinoma (Grawitz Tumor)
01/2024 - 07/2016
6Osteosarcoma (Osteogenic Sarcoma)
01/2024 - 11/2007
6Liver Neoplasms (Liver Cancer)
11/2023 - 01/2019
6Hypotension (Low Blood Pressure)
10/2023 - 10/2020
6Body Weight (Weight, Body)
01/2023 - 05/2006
6COVID-19
11/2022 - 11/2020
6Virus Diseases (Viral Diseases)
11/2020 - 04/2008
6Adenocarcinoma
06/2020 - 10/2016
6Lymphoma (Lymphomas)
01/2020 - 03/2002
6Spinal Cord Injuries (Spinal Cord Injury)
05/2019 - 01/2016
5Ischemic Stroke
01/2024 - 03/2011
5Pain (Aches)
10/2023 - 06/2009
5Type 2 Diabetes Mellitus (MODY)
01/2023 - 08/2006
5Osteolysis
01/2023 - 10/2016
5Osteoarthritis
01/2023 - 11/2017
5Necrosis
11/2022 - 02/2011

Drug/Important Bio-Agent (IBA)

74Proteins (Proteins, Gene)FDA Link
01/2024 - 11/2002
71Biomarkers (Surrogate Marker)IBA
01/2024 - 06/2007
22Messenger RNA (mRNA)IBA
05/2024 - 03/2005
20CytokinesIBA
04/2024 - 04/2008
20MicroRNAs (MicroRNA)IBA
04/2024 - 10/2010
20DNA (Deoxyribonucleic Acid)IBA
02/2024 - 05/2006
17RNA (Ribonucleic Acid)IBA
12/2023 - 05/2016
14EnzymesIBA
04/2024 - 07/2009
14Therapeutic UsesIBA
01/2023 - 06/2009
14carboxyamido-triazole (carboxyamidotriazole)IBA
02/2022 - 05/2006
12Glucose (Dextrose)FDA LinkGeneric
04/2024 - 01/2016
12omega-Chloroacetophenone (Mace)IBA
01/2024 - 09/2018
12Long Noncoding RNAIBA
12/2023 - 05/2016
12Volatile Organic CompoundsIBA
01/2023 - 02/2014
10Phosphotransferases (Kinase)IBA
01/2024 - 04/2014
10Tyrosine Kinase InhibitorsIBA
11/2023 - 08/2016
9LigandsIBA
03/2024 - 01/2018
9VaccinesIBA
11/2022 - 02/2014
9AcidsIBA
01/2022 - 06/2008
8Small Interfering RNA (siRNA)IBA
01/2024 - 01/2010
8LipidsIBA
12/2023 - 08/2016
8OrexinsIBA
01/2022 - 03/2005
7Circular RNAIBA
03/2024 - 01/2020
7Immune Checkpoint InhibitorsIBA
02/2024 - 01/2019
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2024 - 04/2008
7Estrogens (Estrogen)FDA Link
12/2023 - 11/2007
7Norepinephrine (Noradrenaline)FDA LinkGeneric
10/2023 - 10/2020
7Anaplastic Lymphoma KinaseIBA
06/2023 - 08/2013
6CateninsIBA
02/2024 - 05/2010
6Propranolol (Inderal)FDA LinkGeneric
06/2023 - 02/2019
6Indicators and Reagents (Reagents)IBA
10/2022 - 07/2014
6Histones (Histone)IBA
01/2022 - 01/2011
6ChemokinesIBA
01/2021 - 03/2016
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2019 - 04/2008
615-hydroxy-5,8,11,13-eicosatetraenoic acidIBA
11/2010 - 06/2008
5AntigensIBA
12/2023 - 11/2007
5CrizotinibIBA
12/2023 - 06/2015
5Peptides (Polypeptides)IBA
11/2023 - 01/2016
5Cadherins (E-Cadherin)IBA
01/2023 - 04/2010
5InterleukinsIBA
01/2023 - 08/2012
5Hormones (Hormone)IBA
10/2022 - 06/2010

Therapy/Procedure

83Therapeutics
05/2024 - 01/2010
17Immunotherapy
04/2024 - 01/2008
17Drug Therapy (Chemotherapy)
12/2023 - 09/2009
9Neoadjuvant Therapy
01/2022 - 07/2011
6Radiotherapy
12/2022 - 01/2015
5Anesthesia
10/2023 - 10/2020
5Hepatectomy
08/2022 - 08/2014